Nuclear Watchlist Update 10/4/25
ASP Isotopes (ASPI)
Last week, ASPI drew significant market attention after director Todd Wider sold 74,108 shares, sparking discussions about strategic implications of ongoing insider transactions and their impact on sentiment. The company also made headlines for its competitive dual listing on the Johannesburg Stock Exchange and ongoing merger with Renergen, which positions ASPI as a future leader in critical isotopes and helium supply.
Looking ahead, investors are monitoring operational updates and upcoming investor events for clarity on integration milestones and revenue guidance.
BWX Technologies (BWXT)
BWXT announced a major win with a $1.6 billion, 10-year Department of Energy contract for building and operating a high-purity depleted uranium facility in Tennessee. This development further strengthens BWXT’s role in domestic uranium enrichment and national security, and follows recent progress on the Pele microreactor core for the U.S. military, in compliance with Executive Order 14299.
In the coming week, focus will remain on contract execution, local stakeholder engagement for new plant developments, and updates on the microreactor timeline.
Oklo (OKLO)
Oklo shares surged over 500% YTD, with a 51.6% jump in September, driven by its selection for three Department of Energy pilot projects to build advanced fuel fabrication facilities—bolstering its next-generation modular nuclear reactor ambitions. Oklo’s collaboration with Swedish firm Blykalla and groundbreaking of the Aurora reactor reinforce its global leadership positioning in micro-reactor deployment.
Investors are anticipating further details on government support, commercialization timelines, and additional site licensing partnerships in the week ahead.
Constellation Energy (CEG)
CEG accelerated its restart of the Crane Clean Energy Center (formerly Three Mile Island Unit 1) and secured a major 20-year clean power contract with Microsoft, establishing itself as a critical supplier for rapidly growing AI infrastructure demand. The closing of a $7 billion revolving credit line with JPMorgan further solidifies CEG’s growth and acquisition strategy, with analysts highlighting its position as the top U.S. nuclear operator.
The next week could bring updates on the Calpine acquisition and additional long-term power agreements with data center partners.
Cameco (CCJ)
Cameco reported quarterly revenue growth of 46.7% year-over-year, with annual net earnings of $172 million and cash from operations of $905 million, reflecting strength in both uranium production and nuclear fuel services. The company maintained production guidance for its flagship McArthur River/Key Lake and Cigar Lake mines despite brief interruptions, and received continued analyst “Buy” consensus as its stock rallied 64% in 2025.
Upcoming catalysts include further production updates and regulatory filings, as well as any market-moving commentary on supply chain or uranium price trends.
Nano Nuclear Energy (NNE)
NNE’s stock rose 8.4% this week on news of innovative nuclear project partnerships and its addition to both the S&P TMI and S&P Global BMI indices. The company is well-positioned amid U.S. policy moves to quadruple nuclear capacity by 2050, supported by its advanced fuel supply chain and nearly $210 million in cash reserves.
In the week ahead, investor focus will be on progress with project partnerships and any strategic capital announcements.
Centrus Energy (LEU)
LEU surged over 11% as it announced plans to expand its Piketon, Ohio uranium enrichment facility, potentially adding 1,000 construction and 300 permanent jobs, pending federal funding and international partnerships. Recent agreements with Korea Hydro & Nuclear Power and POSCO International signal global confidence in Centrus’s American centrifuge technology.
Investors are watching for finalized funding, progress with permitting, and updates from upcoming investor meetings.
NuScale Power (SMR)
NuScale made headlines for a historic deployment agreement with ENTRA1 Energy and the Tennessee Valley Authority to roll out 6 GW of SMR capacity across seven states—the largest such program in U.S. history. While this milestone expands NuScale’s opportunity set, recent financial concerns such as major shareholder sales and analyst downgrades have fueled short-term volatility.
Potential news in the week ahead includes additional SMR customer contracts, clearer financing paths, and investor reactions to new government policy initiatives.


